1. 
[syn: agnosticism, skepticism, scepticism]
The Collaborative International Dictionary of English v.0.48:
Sceptic \Scep"tic\, Sceptical \Scep"tic*al\, Scepticism
\Scep"ti*cism\, etc.
   See Skeptic, Skeptical, Skepticism, etc.
   [1913 Webster]
The Collaborative International Dictionary of English v.0.48:
Skepticism \Skep"ti*cism\, n. [Cf. F. scepticisme.] [Written
   also scepticism.]
   1. An undecided, inquiring state of mind; doubt; uncertainty.
      [1913 Webster]
            That momentary amazement, and irresolution, and
            confusion, which is the result of skepticism.
                                                  --Hune.
      [1913 Webster]
   2. (Metaph.) The doctrine that no fact or principle can be
      certainly known; the tenet that all knowledge is
      uncertain; Pyrrohonism; universal doubt; the position that
      no fact or truth, however worthy of confidence, can be
      established on philosophical grounds; critical
      investigation or inquiry, as opposed to the positive
      assumption or assertion of certain principles.
      [1913 Webster]
   3. (Theol.) A doubting of the truth of revelation, or a
      denial of the divine origin of the Christian religion, or
      of the being, perfections, or truth of God.
      [1913 Webster]
            Let no . . . secret skepticism lead any one to doubt
            whether this blessed prospect will be realized. --S.
                                                  Miller.
      [1913 Webster]
WordNet (r) 3.0 (2006):
scepticism
    n 1: the disbelief in any claims of ultimate knowledge [syn:
         agnosticism, skepticism, scepticism]