The Collaborative International Dictionary of English v.0.48:

Desecration \Des`e*cra"tion\, n.
   The act of desecrating; profanation; condition of anything
   desecrated.
   [1913 Webster]

WordNet (r) 3.0 (2006):

desecration
    n 1: blasphemous behavior; the act of depriving something of its
         sacred character; "desecration of the Holy Sabbath" [syn:
         profanation, desecration, blasphemy, sacrilege]

Moby Thesaurus II by Grady Ward, 1.0:

48 Moby Thesaurus words for "desecration":
   abomination, abuse, abuse of office, atrocity, befoulment,
   blasphemousness, blasphemy, conversion, corrupt administration,
   debasement, defalcation, defilement, disgrace, diversion,
   embezzlement, fouling, ignominy, impiety, infamy,
   maladministration, malfeasance, malpractice, malversation,
   misapplication, misappropriation, misconduct, misemployment,
   misfeasance, mishandling, mismanagement, misusage, misuse,
   peculation, perversion, pilfering, pity, pollution,
   poor stewardship, profanation, profaneness, profanity,
   prostitution, sacrilege, sacrilegiousness, scandal, shame,
   terrible thing, violation