The Collaborative International Dictionary of English v.0.48:

Vacuolated \Vac"u*o*la`ted\, a. (Biol.)
   Full of vacuoles, or small air cavities; as, vacuolated
   cells.
   [1913 Webster]

WordNet (r) 3.0 (2006):

vacuolated
    adj 1: formed into or containing one or more vacuoles or small
           membrane-bound cavities within a cell [syn: vacuolate,
           vacuolated]