The Collaborative International Dictionary of English v.0.48:

Upshot \Up"shot`\, n. [Up + shot, equivalent to scot share,
   reckoning. Cf. the phrase to cast up an account.]
   Final issue; conclusion; the sum and substance; the end; the
   result; the consummation.
   [1913 Webster]

         I can not pursue with any safety this sport to the
         upshot.                                  --Shak.
   [1913 Webster]

         We account it frailty that threescore years and ten
         make the upshot of man's pleasurable existence. --De
                                                  Quincey.
   [1913 Webster]

WordNet (r) 3.0 (2006):

upshot
    n 1: a phenomenon that follows and is caused by some previous
         phenomenon; "the magnetic effect was greater when the rod
         was lengthwise"; "his decision had depressing consequences
         for business"; "he acted very wise after the event" [syn:
         consequence, effect, outcome, result, event,
         issue, upshot]

Moby Thesaurus II by Grady Ward, 1.0:

85 Moby Thesaurus words for "upshot":
   accomplishment, aftereffect, aftermath, answer, ascertainment,
   backwash, burden, by-product, clearing up, climax, completion,
   conclusion, consequence, consequent, core, corollary, cracking,
   culmination, decipherment, decoding, denouement, derivation,
   derivative, determination, development, disentanglement,
   distillate, effect, end, end result, ending, event, eventuality,
   eventuation, explanation, fallout, feedback, finding, finding-out,
   finish, fruit, gist, harvest, interpretation, issue, legacy,
   logical outcome, meat, offshoot, offspring, outcome, outgrowth,
   pith, precipitate, product, purport, reason, repercussion,
   resolution, resolving, result, resultant, riddling, sense, sequel,
   sequela, sequence, sequent, short, solution, solving, sorting out,
   termination, thrust, unraveling, unriddling, unscrambling,
   unspinning, untangling, untwisting, unweaving, wake, working,
   working-out, wrap-up