The Collaborative International Dictionary of English v.0.48:

Tupelo \Tu"pe*lo\, n. [Tupelo, or tupebo, the native American
   Indian name.] (Bot.)
   A North American tree (Nyssa multiflora) of the Dogwood
   family, having brilliant, glossy foliage and acid red
   berries. The wood is crossgrained and very difficult to
   split. Called also black gum, sour gum, and pepperidge.
   [1913 Webster]

   Largo tupelo, or Tupelo gum (Bot.), an American tree
      (Nyssa uniflora) with softer wood than the tupelo.

   Sour tupelo (Bot.), the Ogeechee lime.
      [1913 Webster]

WordNet (r) 3.0 (2006):

tupelo
    n 1: pale soft wood of a tupelo tree especially the water gum
    2: any of several gum trees of swampy areas of North America
       [syn: tupelo, tupelo tree]
    3: a town in northeast Mississippi

U.S. Gazetteer Places (2000):

Tupelo, AR -- U.S. town in Arkansas
   Population (2000):    177
   Housing Units (2000): 93
   Land area (2000):     0.311330 sq. miles (0.806342 sq. km)
   Water area (2000):    0.000000 sq. miles (0.000000 sq. km)
   Total area (2000):    0.311330 sq. miles (0.806342 sq. km)
   FIPS code:            70340
   Located within:       Arkansas (AR), FIPS 05
   Location:             35.391629 N, 91.229278 W
   ZIP Codes (1990):
   Note: some ZIP codes may be omitted esp. for suburbs.
   Headwords:
    Tupelo, AR
    Tupelo


U.S. Gazetteer Places (2000):

Tupelo, OK -- U.S. city in Oklahoma
   Population (2000):    377
   Housing Units (2000): 178
   Land area (2000):     0.401438 sq. miles (1.039719 sq. km)
   Water area (2000):    0.000000 sq. miles (0.000000 sq. km)
   Total area (2000):    0.401438 sq. miles (1.039719 sq. km)
   FIPS code:            75050
   Located within:       Oklahoma (OK), FIPS 40
   Location:             34.603133 N, 96.420531 W
   ZIP Codes (1990):     74572
   Note: some ZIP codes may be omitted esp. for suburbs.
   Headwords:
    Tupelo, OK
    Tupelo


U.S. Gazetteer Places (2000):

Tupelo, MS -- U.S. city in Mississippi
   Population (2000):    34211
   Housing Units (2000): 14551
   Land area (2000):     51.105468 sq. miles (132.362550 sq. km)
   Water area (2000):    0.318565 sq. miles (0.825079 sq. km)
   Total area (2000):    51.424033 sq. miles (133.187629 sq. km)
   FIPS code:            74840
   Located within:       Mississippi (MS), FIPS 28
   Location:             34.259585 N, 88.725885 W
   ZIP Codes (1990):     38801
   Note: some ZIP codes may be omitted esp. for suburbs.
   Headwords:
    Tupelo, MS
    Tupelo