The Collaborative International Dictionary of English v.0.48:

Refrigerant \Re*frig"er*ant\ (r?*fr?j"?r-ant), a. [L.
   refrigerans, p. pr. of refrigerare: cf. F. r['e]frig['e]rant.
   See Refrigerate.]
   Cooling; allaying heat or fever. --Bacon.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Refrigerant \Re*frig"er*ant\, n.
   That which makes to be cool or cold; specifically, a medicine
   or an application for allaying fever, or the symptoms of
   fever; -- used also figuratively. --Holland. "A refrigerant
   to passion." --Blair.
   [1913 Webster]

WordNet (r) 3.0 (2006):

refrigerant
    adj 1: causing cooling or freezing; "a refrigerant substance
           such as ice or solid carbon dioxide" [syn: refrigerant,
           refrigerating]
    n 1: any substance used to provide cooling (as in a
         refrigerator)

Moby Thesaurus II by Grady Ward, 1.0:

26 Moby Thesaurus words for "refrigerant":
   Dry Ice, Freon, algific, ammonia, blast-freezing, carbon dioxide,
   chilling, congealing, coolant, cooling, ether, ethyl chloride,
   freezable, freezing, freezing mixture, frigorific, glaciable, ice,
   ice cubes, liquid air, liquid helium, liquid oxygen,
   quick-freezing, refrigerative, refrigeratory, sharp-freezing