The Collaborative International Dictionary of English v.0.48:

Pollute \Pol*lute"\, v. t. [imp. & p. p. Polluted; p. pr. &
   vb. n. Polluting.] [L. pollutus, p. p. of polluere to
   defile, to pollute, from a prep. appearing only in comp. +
   luere to wash. See Position, Lave.]
   1. To make foul, impure, or unclean; to defile; to taint; to
      soil; to desecrate; -- used of physical or moral
      defilement.
      [1913 Webster]

            The land was polluted with blood.     --Ps. cvi. 38
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            Wickedness . . . hath polluted the whole earth. --2
                                                  Esd. xv. 6.
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   2. To violate sexually; to debauch; to dishonor.
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   3. (Jewish Law) To render ceremonially unclean; to disqualify
      or unfit for sacred use or service, or for social
      intercourse.
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            Neither shall ye pollute the holy things of the
            children of Israel, lest ye die.      --Num. xviii.
                                                  32.
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            They have polluted themselves with blood. --Lam. iv.
                                                  14.
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   Syn: To defile; soil; contaminate; corrupt; taint; vitiate;
        debauch; dishonor; ravish.
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The Collaborative International Dictionary of English v.0.48:

Pollute \Pol*lute"\, a. [L. pollutus.]
   Polluted. [R.] --Milton.
   [1913 Webster]

WordNet (r) 3.0 (2006):

pollute
    v 1: make impure; "The industrial wastes polluted the lake"
         [syn: pollute, foul, contaminate]

Moby Thesaurus II by Grady Ward, 1.0:

128 Moby Thesaurus words for "pollute":
   abuse, adulterate, afflict, aggrieve, alloy, bastardize, befoul,
   benasty, bewitch, blight, booze up, boozify, canker, cheapen,
   coarsen, condemn, confound, contaminate, convert, corrupt, crock,
   crucify, curse, cut, damage, debase, debauch, defalcate, defile,
   deflower, degenerate, degrade, denaturalize, denature, deprave,
   desecrate, despoil, destroy, devalue, dilute, dirty, disadvantage,
   disserve, distort, distress, divert, do a mischief, do evil,
   do ill, do wrong, do wrong by, doctor, doctor up, doom, embezzle,
   envenom, fortify, foul, fuddle, get into trouble, harass, harm,
   hex, hurt, impair, infect, injure, jinx, lace, maladminister,
   maltreat, menace, mess, mess up, misapply, misappropriate,
   misemploy, mishandle, mismanage, mistreat, misuse, molest, nasty,
   outrage, overtake, peculate, persecute, pervert, pickle, pilfer,
   plaster, play havoc with, play hob with, poison, prejudice,
   profane, prostitute, ravage, ravish, savage, scathe, soil, souse,
   spike, spoil, stain, stew, stone, sully, swack, taint, tamper with,
   tarnish, threaten, tipsify, torment, torture, twist, ulcerate,
   violate, vitiate, vulgarize, warp, water, water down, wound,
   wreak havoc on, wrong