The Collaborative International Dictionary of English v.0.48:

Misuse \Mis*use"\ (m[i^]s*[=u]z"), v. t. [F. m['e]suser. See
   Mis-, prefix from French, and Use.]
   1. To treat or use improperly; to use to a bad purpose; to
      misapply; as, to misuse one's talents. --South.
      [1913 Webster]

            The sweet poison of misused wine.     --Milton.
      [1913 Webster]

   2. To abuse; to treat ill.
      [1913 Webster]

            O, she misused me past the endurance of a block.
                                                  --Shak.
      [1913 Webster]

   Syn: To maltreat; abuse; misemploy; misapply.
        [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Misuse \Mis*use"\ (m[i^]s*[=u]s"), n.
   1. Wrong use; misapplication; erroneous or improper use.
      [1913 Webster]

            Words little suspected for any such misuse. --Locke.
      [1913 Webster]

   2. Violence, or its effects. [Obs.] --Shak.
      [1913 Webster]

WordNet (r) 3.0 (2006):

misuse
    n 1: improper or excessive use; "alcohol abuse"; "the abuse of
         public funds" [syn: misuse, abuse]
    v 1: apply to a wrong thing or person; apply badly or
         incorrectly; "The words are misapplied in this context";
         "You are misapplying the name of this religious group"
         [syn: misapply, misuse]
    2: change the inherent purpose or function of something; "Don't
       abuse the system"; "The director of the factory misused the
       funds intended for the health care of his workers" [syn:
       pervert, misuse, abuse]

Moby Thesaurus II by Grady Ward, 1.0:

169 Moby Thesaurus words for "misuse":
   abuse, active use, adulterate, adulteration, alloy, appliance,
   application, barbarism, befoul, befouling, bias, bleed,
   bleed white, canker, catachresis, cheapen, clerical error, coarsen,
   color, confound, consumption, contaminate, contamination, convert,
   corrigendum, corrupt, corruption, debase, debauch, defalcate,
   defile, defilement, deflower, degenerate, degrade, denature,
   deprave, desecrate, despoil, devalue, distort, diversion, divert,
   diverting, do amiss, drain, embezzle, employ, employment,
   envenoming, erratum, error, exercise, exertion, exploit, failure,
   false coloring, fault, faute, festering, foul, fouling, garble,
   good use, hard usage, hard use, human error, ill use, ill-treat,
   ill-use, impose upon, infect, infection, infelicity, make use of,
   maladminister, malapropism, maltreat, manipulate, milk,
   misapplication, misapply, misapprehension, misappropriate,
   misappropriation, miscalculation, miscall, miscarriage, miscite,
   misconception, misconduct, misconstruction, misconstrue, miscount,
   misdeal, misdirect, misdirection, misemploy, misemployment,
   misfield, mishandle, misidentification, misinterpret,
   misinterpretation, misjudgment, mismanage, misplay, misprint,
   misquotation, misquote, misread, misrender, misreport,
   misrepresent, misrepresentation, miss, misspell, misstatement,
   mistake, mistreat, mistreatment, misunderstanding, misusage,
   outrage, peculate, perversion, pervert, pilfer, play on, poison,
   poisoning, pollute, pollution, presume upon, profane, prostitute,
   prostitution, ravage, ravish, rough usage, slant, slanting,
   solecism, strain, straining, stroke, suck dry, suppuration, taint,
   take advantage of, torture, torturing, twist, typo,
   typographical error, ulcerate, usage, use, use ill, using up,
   varnish, violate, vitiate, vitiation, vulgarize, warp, work on,
   work upon, wrong use