The Collaborative International Dictionary of English v.0.48:

Extirpation \Ex`tir*pa"tion\, n. [L. extirpatio, exstirpatio:
   cf. F. extirpation.]
   The act of extirpating or rooting out, or the state of being
   extirpated; eradication; excision; total destruction; as, the
   extirpation of weeds from land, of evil from the heart, of a
   race of men, of heresy.
   [1913 Webster]

WordNet (r) 3.0 (2006):

extirpation
    n 1: surgical removal of a body part or tissue [syn: ablation,
         extirpation, cutting out, excision]
    2: the act of pulling up or out; uprooting; cutting off from
       existence [syn: extirpation, excision, deracination]