The Collaborative International Dictionary of English v.0.48:

Vesicate \Ves"i*cate\, v. t. [imp. & p. p. Vesicated; p. pr. &
   vb. n. Vesicating.] [See Vesicant.] (Med.)
   To raise little bladders or blisters upon; to inflame and
   separate the cuticle of; to blister. --Wiseman.
   [1913 Webster]