The Collaborative International Dictionary of English v.0.48:
Spite \Spite\, n. [Abbreviated fr. despite.]
1. Ill-will or hatred toward another, accompanied with the
disposition to irritate, annoy, or thwart; petty malice;
grudge; rancor; despite. --Pope.
This is the deadly spite that angers. --Shak.
2. Vexation; chargrin; mortification. [R.] --Shak.
In spite of, or Spite of, in opposition to all efforts
of; in defiance or contempt of; notwithstanding.
"Continuing, spite of pain, to use a knee after it had
been slightly injured." --H. Spenser. "And saved me in
spite of the world, the devil, and myself." --South. "In
spite of all applications, the patient grew worse every
day." --Arbuthnot. See Syn. under Notwithstanding.
To owe one a spite, to entertain a mean hatred for him.
Syn: Pique, rancor; malevolence; grudge.
Usage: Spite, Malice. Malice has more reference to the
disposition, and spite to the manifestation of it in
words and actions. It is, therefore, meaner than
malice, thought not always more criminal. " Malice . .
. is more frequently employed to express the
dispositions of inferior minds to execute every
purpose of mischief within the more limited circle of
their abilities." --Cogan. "Consider eke, that spite
availeth naught." --Wyatt. See Pique.