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The Collaborative International Dictionary of English v.0.48:

Sophisticate \So*phis"ti*cate\, v. t. [imp. & p. p. Sophisticated; p. pr. & vb. n. Sophisticating.] [LL. sophisticatus, p. p. of sophisticare to sophisticate.] To render worthless by admixture; to adulterate; to damage; to pervert; as, to sophisticate wine. --Howell. [1913 Webster] To sophisticate the understanding. --Southey. [1913 Webster] Yet Butler professes to stick to plain facts, not to sophisticate, not to refine. --M. Arnold. [1913 Webster] They purchase but sophisticated ware. --Dryden. [1913 Webster] Syn: To adulterate; debase; corrupt; vitiate. [1913 Webster] Sophisticate