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The Collaborative International Dictionary of English v.0.48:

Slough \Slough\, v. i. [imp. & p. p. Sloughed; p. pr. & vb. n. Sloughing.] (Med.) To form a slough; to separate in the form of dead matter from the living tissues; -- often used with off, or away; as, a sloughing ulcer; the dead tissues slough off slowly. [1913 Webster]