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The Collaborative International Dictionary of English v.0.48:

Mestizo \Mes*ti"zo\, n.; pl. Mestizos. [Sp. mestizo; akin to OF. mestis, F. m['e]tis; all fr. (assumed) LL. mixtitius, fr. L. mixtus mixed, p. p. of miscere to mix. See Mix, and cf. Mestee, M['e]tif, M['e]tis, Mustee.] The offspring of an Indian or a negro and a European or person of European stock. [Spanish America] [1913 Webster] Mestizo wool, wool imported from South America, and produced by mixed breeds of sheep. [1913 Webster]