The Collaborative International Dictionary of English v.0.48:

Macule \Mac"ule\, n. [F. macule. See Macula.]
   1. A spot. [Obs.]
      [1913 Webster]

   2. (Print.) A blur, or an appearance of a double impression,
      as when the paper slips a little; a mackle.
      [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Macule \Mac"ule\, v. t. [Cf. F. maculer. See Maculate, v.]
   To blur; especially (Print.), to blur or double an impression
   from type. See Mackle.
   [1913 Webster]

The Collaborative International Dictionary of English v.0.48:

Macula \Mac"u*la\, n.; pl. Maculae. [L., spot, stain, blot.
   See Mail armor, and cf. Mackle, Macule.]
   1. A spot, as on the skin, or on the surface of the sun or of
      some other luminous orb; called also macule.
      [1913 Webster]

   2. (Zool.) A rather large spot or blotch of color.
      [1913 Webster] macula lutea

WordNet (r) 3.0 (2006):

macule
    n 1: a patch of skin that is discolored but not usually
         elevated; caused by various diseases [syn: macule,
         macula]