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The Collaborative International Dictionary of English v.0.48:

Exasperate \Ex*as"per*ate\, v. t. [imp. & p. p. Exsasperated; p. pr. & vb. n. Exasperating.] 1. To irritate in a high degree; to provoke; to enrage; to excite or to inflame the anger of; as, to exasperate a person or his feelings. [1913 Webster] To exsasperate them against the king of France. --Addison. [1913 Webster] 2. To make grievous, or more grievous or malignant; to aggravate; to imbitter; as, to exasperate enmity. [1913 Webster] To exasperate the ways of death. --Sir T. Browne. Syn: To irritate; provoke. See Irritate. [1913 Webster]