The Collaborative International Dictionary of English v.0.48:
Astute \As*tute"\, a. [L. astutus, fr. astus craft, cunning;
perh. cognate with E. acute.]
Critically discerning; sagacious; shrewd; subtle; crafty.
Syn: Keen; eagle-eyed; penetrating; skilled; discriminating;
cunning; sagacious; subtle; wily; crafty.
[1913 Webster] As*tute"ly, adv. -- As*tute"ness, n.
Moby Thesaurus II by Grady Ward, 1.0:
94 Moby Thesaurus words for "astute":
Machiavellian, Machiavellic, acute, adroit, alert, apperceptive,
appercipient, arch, argute, artful, cagey, calculating, canny,
clever, cogent, crafty, cunning, cute, deceitful, deep, deep-laid,
designing, diplomatic, discerning, discreet, farseeing, farsighted,
feline, foreseeing, foresighted, forethoughted, forethoughtful,
foxy, guileful, heady, incisive, ingenious, insidious, insightful,
intelligent, inventive, judicious, keen, knowing, knowledgeable,
longheaded, longsighted, observant, pawky, penetrating, perceptive,
percipient, perspicacious, perspicuous, piercing, politic,
provident, prudent, quick, quick-witted, ready, resourceful,
sagacious, sage, savvy, scheming, serpentine, sharp, shifty,
shrewd, slick, slippery, sly, smooth, snaky, sneaky, sophistical,
stealthy, strategic, subtile, subtle, supple, tactical, trenchant,
trickish, tricksy, tricky, underhand, underhanded, understanding,
vulpine, wary, wily, wise