The Collaborative International Dictionary of English v.0.48:
Anathema \A*nath"e*ma\, n.; pl. Anathemas. [L. anath[e^]ma,
fr. Gr. ? anything devoted, esp. to evil, a curse; also L.
anath[=e]ma, fr. Gr. ? a votive offering; all fr. ? to set up
as a votive gift, dedicate; ? up + ? to set. See Thesis.]
1. A ban or curse pronounced with religious solemnity by
ecclesiastical authority, and accompanied by
excommunication. Hence: Denunciation of anything as
[They] denounce anathemas against unbelievers.
2. An imprecation; a curse; a malediction.
Finally she fled to London followed by the anathemas
of both [families]. --Thackeray.
3. Any person or thing anathematized, or cursed by
The Jewish nation were an anathema destined to
destruction. St. Paul . . . says he could wish, to
save them from it, to become an anathema, and be
destroyed himself. --Locke.
Anathema Maranatha(see --1 Cor. xvi. 22), an expression
commonly considered as a highly intensified form of
anathema. Maran atha is now considered as a separate
sentence, meaning, "Our Lord cometh."
[1913 Webster] Anathematic