The Collaborative International Dictionary of English v.0.48:
Variola \Va*ri"o*la\, n. [LL., fr. L. varius various. See Various.] (Med.) The smallpox. [1913 Webster]WordNet (r) 3.0 (2006):
variola n 1: a highly contagious viral disease characterized by fever and weakness and skin eruption with pustules that form scabs that slough off leaving scars [syn: smallpox, variola, variola major]