NOUN (2)

1. rejection by God; the state of being condemned to eternal misery in Hell;

2. severe disapproval;

The Collaborative International Dictionary of English v.0.48:

Reprobation \Rep`ro*ba"tion\ (-b?`sh?n), n. [F. r['e]probation,
   or L. reprobatio.]
   1. The act of reprobating; the state of being reprobated;
      strong disapproval or censure.
      [1913 Webster]

            The profligate pretenses upon which he was
            perpetually soliciting an increase of his
            disgraceful stipend are mentioned with becoming
            reprobation.                          --Jeffrey.
      [1913 Webster]

            Set a brand of reprobation on clipped poetry and
            false coin.                           --Dryden.
      [1913 Webster]

   2. (Theol.) The predestination of a certain number of the
      human race as reprobates, or objects of condemnation and
      punishment.
      [1913 Webster]

WordNet (r) 3.0 (2006):

reprobation
    n 1: rejection by God; the state of being condemned to eternal
         misery in Hell
    2: severe disapproval

The Devil's Dictionary (1881-1906):

REPROBATION, n.  In theology, the state of a luckless mortal
prenatally damned.  The doctrine of reprobation was taught by Calvin,
whose joy in it was somewhat marred by the sad sincerity of his
conviction that although some are foredoomed to perdition, others are
predestined to salvation.