1. a Christian heresy of the 5th and 6th centuries that challenged the orthodox definition of the two natures (human and divine) in Jesus and instead believed there was a single divine nature;
WordNet (r) 3.0 (2006):
Monophysitism
n 1: a Christian heresy of the 5th and 6th centuries that
challenged the orthodox definition of the two natures
(human and divine) in Jesus and instead believed there was
a single divine nature