The Collaborative International Dictionary of English v.0.48:
Manipulate \Ma*nip"u*late\, v. t. [imp. & p. p. Manipulated;
p. pr. & vb. n. Manipulating.] [LL. manipulatus, p. p. of
manipulare to lead by the hand, fr. L. manipulus. See
1. To treat, work, or operate with the hands, especially when
knowledge and dexterity are required; to manage in hand
work; to handle; as, to manipulate scientific apparatus.
2. To control the action of, by management; as, to manipulate
a convention of delegates; also, to manage artfully or
fraudulently; as, to manipulate accounts, or election
returns; to manipulate the stock market.