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The Collaborative International Dictionary of English v.0.48:

Manipulate \Ma*nip"u*late\, v. t. [imp. & p. p. Manipulated; p. pr. & vb. n. Manipulating.] [LL. manipulatus, p. p. of manipulare to lead by the hand, fr. L. manipulus. See Maniple.] 1. To treat, work, or operate with the hands, especially when knowledge and dexterity are required; to manage in hand work; to handle; as, to manipulate scientific apparatus. [1913 Webster] 2. To control the action of, by management; as, to manipulate a convention of delegates; also, to manage artfully or fraudulently; as, to manipulate accounts, or election returns; to manipulate the stock market. [1913 Webster]