NOUN (1)

1. a person afflicted with manic-depressive illness;


ADJECTIVE (1)

1. suffering from a disorder characterized by alternating mania and depression;

The Collaborative International Dictionary of English v.0.48:

manic-depressive \manic-depressive\ n. (Med.),
   A person suffering from manic-depressive psychosis.
   [PJC]

WordNet (r) 3.0 (2006):

manic-depressive
    adj 1: suffering from a disorder characterized by alternating
           mania and depression
    n 1: a person afflicted with manic-depressive illness