The Collaborative International Dictionary of English v.0.48:

Half-blooded \Half"-blood`ed\, a.
   1. Proceeding from a male and female of different breeds or
      races; having only one parent of good stock; as, a
      half-blooded sheep.
      [1913 Webster]

   2. Degenerate; mean. --Shak.
      [1913 Webster]

WordNet (r) 3.0 (2006):

half-blooded
    adj 1: (of animals) having only one purebred parent [syn: half-
           blooded, half-bred, half-breed]