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The Collaborative International Dictionary of English v.0.48:

Disinure \Dis`in*ure"\, v. t. [imp. & p. p. Disinured; p. pr. & vb. n. Disinuring.] [Pref. dis- + inure.] To render unaccustomed or unfamiliar. [1913 Webster] We are hindered and disinured . . . towards the true knowledge. --Milton. [1913 Webster]