The Collaborative International Dictionary of English v.0.48:

Ayrshire \Ayr"shire\, n. (Agric.)
   One of a superior breed of cattle from Ayrshire, Scotland.
   Ayrshires are notable for the quantity and quality of their
   milk.
   [1913 Webster]

WordNet (r) 3.0 (2006):

Ayrshire
    n 1: hardy breed of dairy cattle from Ayr, Scotland

U.S. Gazetteer Places (2000):

Ayrshire, IA -- U.S. city in Iowa
   Population (2000):    202
   Housing Units (2000): 98
   Land area (2000):     0.208116 sq. miles (0.539018 sq. km)
   Water area (2000):    0.000000 sq. miles (0.000000 sq. km)
   Total area (2000):    0.208116 sq. miles (0.539018 sq. km)
   FIPS code:            04105
   Located within:       Iowa (IA), FIPS 19
   Location:             43.038506 N, 94.834712 W
   ZIP Codes (1990):     50515
   Note: some ZIP codes may be omitted esp. for suburbs.
   Headwords:
    Ayrshire, IA
    Ayrshire