The Collaborative International Dictionary of English v.0.48:
Offend \Of*fend"\, v. i.
1. To transgress the moral or divine law; to commit a crime;
to stumble; to sin.
Whosoever shall keep the whole law, and yet offend
in one point, he is guilty of all. --James ii.
If it be a sin to covet honor,
I am the most offending soul alive. --Shak.
2. To cause dislike, anger, or vexation; to displease.
I shall offend, either to detain or give it. --Shak.
To offend against, to do an injury or wrong to; to commit
an offense against. "We have offended against the Lord
already." --2 Chron. xxviii. 13.