The Collaborative International Dictionary of English v.0.48:

Mortification \Mor`ti*fi*ca"tion\, n. [F., fr. L. mortificatio a
   killing. See Mortify.]
   1. The act of mortifying, or the condition of being
      mortified; especially:
      (a) (Med.) The death of one part of an animal body, while
          the rest continues to live; loss of vitality in some
          part of a living animal; gangrene. --Dunglison.
      (b) (Alchem. & Old Chem.) Destruction of active qualities;
          neutralization. [Obs.] --Bacon.
      (c) Subjection of the passions and appetites, by penance,
          abstinence, or painful severities inflicted on the
          body.
          [1913 Webster]

                The mortification of our lusts has something in
                it that is troublesome, yet nothing that is
                unreasonable.                     --Tillotson.
          [1913 Webster]

   2. Deep humiliation or shame, from a loss of pride; painful
      embarassment, usually arising from exposure of a mistake;
      chagrin; vexation.
      [1913 Webster +PJC]

   3. That which mortifies; the cause of humiliation, chagrin,
      or vexation.
      [1913 Webster]

            It is one of the vexatious mortifications of a
            studious man to have his thoughts discovered by a
            tedious visit.                        --L'Estrange.
      [1913 Webster]

   4. (Scots Law) A gift to some charitable or religious
      institution; -- nearly synonymous with mortmain.
      [1913 Webster]

   Syn: Chagrin; vexation; shame. See Chagrin.
        [1913 Webster]

WordNet (r) 3.0 (2006):

mortification
    n 1: strong feelings of embarrassment [syn: chagrin,
         humiliation, mortification]
    2: the localized death of living cells (as from infection or the
       interruption of blood supply) [syn: necrosis,
       mortification, gangrene, sphacelus]
    3: an instance in which you are caused to lose your prestige or
       self-respect; "he had to undergo one humiliation after
       another" [syn: humiliation, mortification]
    4: (Christianity) the act of mortifying the lusts of the flesh
       by self-denial and privation (especially by bodily pain or
       discomfort inflicted on yourself)

Moby Thesaurus II by Grady Ward, 1.0:

96 Moby Thesaurus words for "mortification":
   Albigensianism, Catharism, Day of Atonement, Franciscanism,
   Sabbatarianism, Trappism, Waldensianism, Yoga, Yom Kippur,
   abasement, abashment, abstinence, anchoritic monasticism,
   anchoritism, asceticism, austerity, awkwardness, caries, carrion,
   chagrin, cold purgatorial fires, comedown, confusion, debasement,
   decay, decomposition, deflation, descent, discomfiture,
   discomposure, disconcertedness, disconcertion, disconcertment,
   discountenance, disgrace, distress, disturbance, dry gangrene,
   dry rot, dump, embarrassment, eremitism, fasting, flagellation,
   foulness, gangrene, gas gangrene, hair shirt, hangdog look,
   humbled pride, humiliation, letdown, lustration, maceration,
   mendicantism, moist gangrene, monachism, monasticism, necrosis,
   necrotic tissue, noma, penance, penitence, penitential act,
   penitential exercise, purgation, purgatory, puritanism, put-down,
   putrefaction, putrescence, putridity, putridness, rancidity,
   rancidness, rankness, repentance, rigor, rot, rottenness,
   sackcloth and ashes, self-abasement, self-abnegation, self-denial,
   self-diminishment, self-mortification, setdown, shame,
   shamefacedness, shamefastness, slough, sphacelation, sphacelus,
   spoilage, tooth decay, voluntary poverty



Bouvier's Law Dictionary, Revised 6th Ed (1856):

MORTIFICATION, Scotch law. This term is nearly synonymous with mortmain.